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氯胺酮对认知影响的机制 被引量：4

The mechanisms of ketamine impairments on cognition
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摘要 氯胺酮是NMDA受体的非竞争性拮抗剂。研究显示，它能够损伤工作记忆、情节记忆和语义记忆并且伴随着精神症状和分离幻觉的出现，揭示其对认知功能有影响。它可能通过NMDA受体、烟碱受体、GABA和GABA受体、钠通道干扰长时程增强（long-term potentiation，LTP）的功能，从而影响认知功能。
作者 渠兴乾 程志军 沈伯雄 杭燕南
机构地区 上海交通大学医学院附属第三人民医院麻醉科 上海交通大学医学院附属仁济医院麻醉科
出处 《国际麻醉学与复苏杂志》 CAS 2009年第1期45-47,共3页 International Journal of Anesthesiology and Resuscitation
关键词 氯胺酮 认知 LTP GABA 钠通道 Ketamine Cognition LTP GABA Sodium channel
分类号 R74 [医药卫生—神经病学与精神病学]
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参考文献18

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二级参考文献8

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共引文献17

同被引文献29

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  • 2陈平,黄亚辉,金文杰,王玲,钱燕宁.舒芬太尼或氯胺酮预先给药对成人静脉血辅助性T淋巴细胞分化的影响[J].中华麻醉学杂志,2006,26(5):397-400. 被引量：18
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引证文献4

二级引证文献14

国际麻醉学与复苏杂志
2009年 第1期

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