摘要
本实验在大脑中动脉阻塞(MCAO)及再灌注动物模型上,观察缺血后电针对大鼠体感诱发电位(SEP)和脑梗塞体积的影响。结果发现缺血组和缺血后电针组在MCAO后30分钟,缺血侧SEP波幅降至缺血前的2.2±3%,1.9±2%,缺血后再灌注7天,SEP恢复至缺血前的25.5±14.1%,58.6±27.2%,两组比较P<0.05;脑梗塞体积分别为70.72±25.4mm3,45.65±11.4mm3(P<0.05)。结果提示电针可促进脑缺血后SEP的恢复,减少脑缺血性组织坏死。
The model of reversible middle cerebral artery occlusion(MCAO) was used to study the effect of electroacupuncture(EA) on somatosensory evoked potential (SEP) and infarct volume after MCAO in rats. After 1 hour of MCAO, EA was applied at the points of Fengfu(DU 16)and Renzhong(DU 26).The results were as follows: (1) In MCAO group and MCAO + EA group the amplitude of SEP on the ipsilateral side of MCAO was nearly abolished at 30 min after MCAO and recovered to 25.5±14.1%,58. 6±27. 2 % (P <0.05)on day 7 after reperfusion. (2) The infarct volume in MCAO group and EA + MCAO group was 70. 72±25. 4mm3, 45. 65±11. 4mm3 (P <0.05) respectively after reperfusion 7 days following MCAO 2 hours.The results above indicate that EA might produce cerebroprotective effect after focal cerebral ischemia.
出处
《针刺研究》
CAS
CSCD
1998年第1期36-40,共5页
Acupuncture Research