老年肝硬化并发多器官功能衰竭

Studies on elderly cirrhosis patients complicated with multiple organ failure

目的了解老年肝硬化患者并发多器官功能衰竭（ＭＯＦ）的情况，探讨其诱发因素及防治方法。方法对本院１９９１～１９９５年住院老年肝硬化患者２００例进行回顾性调查。结果老年肝硬化并发ＭＯＦ的发生率为１８％（３６／２００），病死率６３．９％（２３／３６）。诱发因素中以感染占首位，累及的器官主要有中枢神经系统、胃肠道、肾脏等，随着累及器官的增加，病死率也增加。结论老年肝硬化ＭＯＦ发生率较高，发生ＭＯＦ的病死率极高。

Objective To study multiple organ failure(MOF) in elderly cirrhosis patients and investigate its precipitating factors. Methods The clinical data of 200 elderly patients with cirrhosis were retrospectively in vestigated. Results The incidence of MOF in elderly patients with cirrhosis was 18%(36/200)and its mortality rate was 63 8%(23/36).Infection was the major precipitating cause of MOF.The failed organs were central nervous system,gastrointestinal tract,kidneys,et al.The mortality rate increased as the number of failed organs increased. Conclusions The incidence of MOF was high in elderly cirrhosis patients.MOF significantly affected the prognosis of elderly patients with cirrhosis.