颅脑B超对围产期缺氧性脑损伤后脑萎缩性改变的诊断价值

EVALUATION OF CRANIAL ULTRASOUND TECHNIQUE IN DIAGNOSING CEREBRAL ATROPHY AFTER PERINATAL HYPOXIC BRAIN DAMAGE

为了解围产期缺氧性脑损伤后脑萎缩的B超影像特点，对23例有明确缺氧史的小儿及53例正常儿在3个月左右进行颅脑B超检查及对比。不同断面脑正中裂宽度与侧脑室深度测量数值在两组间差异显著，缺氧组异常增宽率高于对照组（69．56％及13．21％，P＜0．01），脑沟回形态改变发生率多于正常组（82．61％及11．32％），二者符合率73．68％。结论：颅脑B超可作为早期了解脑损伤后萎缩性改变的手段，有益于进一步估价预后及早期干预。

To investigate the characteristic image features of cerebral atrophy after perinatal hypoxic brain damage, cranial ultrasound and comparative analysis were performed at about three Wonths after birth in 23 babies with perinatal hypoxic history and 53 normal babies.The width of cerebral central fissures and the depth of lateral ventricles were measured at different scanning sections. We found that the central fissure extending rate was higher in the hypoxic group than that in the control (69. 56% and 13. 21%). The morphological changes of gyrus in hypoxic group were also more frequently seen than in the control (82. 61 % and 11.32%). The widening of central fissures often co-existed with thecerebral morphological changes, and the identical rate was 73. 68%. We therefore conclude that cranial ultrasound can be a new diagnostic approach for early detection of cerebral atrophy after perinatal hypoxic brain damage. It is also a useful technique in prognostic evaluation and for early intervention