2008年我院150例外科围手术期患者抗菌药物应用分析

Perioperative Use of Antibiotic in Our Hospital in 2008:Analysis of 150 Cases

目的:了解我院外科围手术期患者抗菌药物的应用情况。方法:对我院2008年8月～9月的150例外科围手术期患者(Ⅰ类切口50例,Ⅱ类切口100例)的用药情况进行回归顾性分析。结果:Ⅰ类手术中头孢菌素类应用频率最高,其次依次为氟喹诺酮类、青霉素类、克林霉素类。结论:围手术期抗菌药物选择合理率过低,Ⅰ类清洁手术术后抗菌药物使用时间过长,应加强临床医务人员围手术期抗菌药物合理化使用的意识,有效地降低围手术期切口的感染率和耐药菌的发生率。

OBJECTIVE： To probe into the utilization situation of the antibiotic in surgery patients during perioperative period in our hospital. METHODS： The perioperative utilization of antibiotics in 150 surgery patients （50 cases with type Ⅰ incision and 100 type Ⅱ incision） in our hospital between August and September in 2008 were analyzed retrospectively. RESULTS： For type Ⅰ surgery, cephalosporins took the lead in terms of DDDs, followed in turn by quinolones, penicillins and Clindamycin. CONCLUSION： The antibiotic selection was at very low level of rationality and the postoperative medication duration of antibiotics in type Ⅰ incision surgery was too long. It is necessary to strengthen the consciousness of clinicians about the rational use of antibiotics during perioperative period so as to effectively lower the infection rate and the incidence of dragresistance bacteria.