青少年慢性肾脏病患者血管内膜中膜厚度变化与胎球蛋白-A的关系
摘要
慢性肾脏病(CKD)患者和正常人群相比过早的发生动脉粥样硬化和血管硬化。在这类患者中,血管壁的改变不仅在成年人中发生,也可在青少年中发生。在儿童慢性肾脏病患者中,35%~50%的死亡人数是由心血管疾病造成的,依靠透析治疗而生存下来的青年儿童数目不断增加,资料表明随着时间的延长,会激发影响其长期预后的动脉变化。高分辨率颈动脉超声是一种能够评估成人和儿童血管改变的有效方法,无论在一般人群中还是在终末期肾脏病患者中,
出处
《中国血液净化》
2009年第2期98-100,共3页
Chinese Journal of Blood Purification
参考文献11
-
1Nayir A, Bilge I, Kilicaslan I, et al. Arterial changes in paediatric haemodialysis patients undergoing renal transplantation[J]. Nephrol Dial Transplant, 2001,16:2041- 2047.
-
2McDonald SP, Craig JC .Long-term survival of children with end-stage renal disease[J]. N Engl J Med ,2004, 350: 2654-2662.
-
3艾乙,夏青.正常儿童颈动脉双功能彩色多普勒检测值研究[J].中国儿童保健杂志,2004,12(1):20-22. 被引量:10
-
4GoodmanWG, Goldia J, Kuizon BD, et al. Coronary-artery calcification in young adults with endstage renal disease who are undergoing dialysis[J]. N Engl J Med, 2000,342: 1478-1448.
-
5Tamashiro M, Iseki K, Sunagawa O, et al. Significant association between progression of coronary artery calcification and dyslipidemia in patients on chronic hemodialysis[J]. Am J Kidney Dis, 2001,38:64-69.
-
6姚英,刘惠兰,王银娜,刘群.血液透析患者血磷水平与颈动脉内-中膜厚度的关系[J].中国血液净化,2007,6(8):411-414. 被引量:12
-
7Reynolds JL, Joannides AJ, Skepper JN, et al. Human vascular smooth muscle cells undergo vesiclemediated cal- cification in response to changes in extracellular calcium and phosphate concentrations: a potential mechanism for accelerated vascular calcification in ESRD[J]. J Am Soc Nephrol, 2004, 15:2857-2867
-
8Ketteler M,Bongartz P, Westenfeld R, et al. Association of low fetuin-A(AHSG)concentrations in serum with cardiovascular mortality in patients on dialysis:a cross-sectional study[J].Lancet, 2003,361(9360):827-833.
-
9梁馨苓,史伟,章斌,刘双信,林秋雄,黄美萍,王文健,叶智明,何朝生.终末期肾病患者心血管事件与血清胎球蛋白A及冠脉钙化的关系[J].中华肾脏病杂志,2006,22(6):336-340. 被引量:25
-
10王开 ,钱家麒 ,Peter Stenvinkel ,Bengt Lindholm .终末期肾衰竭患者血清胎球蛋白A水平改变与临床预后的关系[J].中华肾脏病杂志,2005,21(2):72-75. 被引量:21
二级参考文献52
-
1王开 ,钱家麒 ,Peter Stenvinkel ,Bengt Lindholm .终末期肾衰竭患者血清胎球蛋白A水平改变与临床预后的关系[J].中华肾脏病杂志,2005,21(2):72-75. 被引量:21
-
2Goodman WG, Goldin J, Kuizon BD, et al. Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Engl J Med, 2000,342:1478-1483.?A?A?A
-
3Schinke T, Amendt C, Trindl A, et al. The serum protein alpha2-HS glycoprotein/fetuin inhibites apatite formation in vitro and in mineralizing calvaria cells: a possible role in mineralization and calcium homeostasis. J Biol Chem, 1996,271: 20789-20796.
-
4Jahnen-Dechent W, Schinke T, Trindl A, et al. Cloning and targeted deletion of the mouse fetuin gene. J Biol Chem,1997,272: 31496-31503.
-
5Schinke T, Karsenty G. Vascular calcffication-a passive process in need of inhibitors. Nephrol Dial Transplant, 2000, 15:1272-1274.
-
6Binkert C, Dementriou M, Sukhu B, et al. Regulation of osteogenesis by fetuin. J Biol Chem, 1999, 274:28514-28520.
-
7Ruminy P, Gangneux C, Claeyssens S, et al. Gene transcription in hepatocytes during the acute phase of a systemic inflammation: from transcription factors to target genes. Inflamm Res, 2001, 50:383-390.
-
8Ombrellino M, Wang H, Yang H, et al. Fetuin, a negative acute phase protein, attenuates TNF synthesis and the innate inflammatory response to carrageenan. Shock, 2001, 15:181-185.
-
9Wang H, Zhang M, Bianchi M, et al. Fetuin (alpha2-HS-glycoprotein) opsonizes cationic macrophagedeactivating molecules. Proc Natl Acad Sci USA, 1998, 95:14429-14434.
-
10Mathews ST, Chellam N, Srinivas PR, et al. Alpha2-HSG, a specific inhibitor of insulin receptor autophosphorylation,interacts with the insulin receptor. Mol Cell Endocrinol, 2000,164:87-98.
共引文献78
-
1陈昕,彭波,陈明.终末期肾病患者血管钙化与钙化抑制物[J].国际泌尿系统杂志,2006,26(1):132-135. 被引量:1
-
2张力,米杰,程红,赵小元,候冬青,单晓益.学龄儿童动脉顺应性的年龄性别分布及相关因素[J].中国循环杂志,2006,21(2):121-124. 被引量:4
-
3梁馨苓,史伟,章斌,刘双信,林秋雄,黄美萍,王文健,叶智明,何朝生.终末期肾病患者心血管事件与血清胎球蛋白A及冠脉钙化的关系[J].中华肾脏病杂志,2006,22(6):336-340. 被引量:25
-
4YANG Xiao-zheng,LIU Ying,MI Jie,TANG Chao-shu,DU Jun-bao.Pre-clinical atherosclerosis evaluated by carotid artery intimamedia thickness and the risk factors in children[J].Chinese Medical Journal,2007(5):359-362. 被引量:1
-
5王宓,王梅,甘良英,李四君,张萌.血液透析患者血浆胎球蛋白A水平及其与血管钙化的关系[J].中国血液净化,2007,6(5):263-266. 被引量:22
-
6刘颖,张玉林,王峥嵘,唐朝枢,杜军保.颈动脉超声技术与儿童临床前动脉粥样硬化危险因素[J].中国动脉硬化杂志,2006,14(12):1041-1044. 被引量:4
-
7莫晓冬,赵慧萍.慢性肾脏疾病血管钙化的病因及发病机制[J].广东医学,2007,28(10):1713-1715. 被引量:2
-
8袁自宏,周健美.终末期肾病患者的血管钙化与骨调节蛋白[J].实用药物与临床,2007,10(5):298-300.
-
9陈泠希,孙明.Fetuin-A与代谢综合征可能机制之间的联系[J].医学临床研究,2007,24(10):1802-1804.
-
10袁自宏,周健美,姚少峰,陈兵.不同钙浓度透析液对高磷血症血液透析患者钙磷代谢和血清胎球蛋白A水平的影响[J].内科理论与实践,2008,3(1):41-44. 被引量:2
-
1倪广臻,孙西锋,潘祥坡,李世荣,魏成军.慢性肾病患者血脂蛋白(a)和纤维蛋白原与颈动脉硬化的相关性[J].中国动脉硬化杂志,2015,23(10):1039-1042. 被引量:1
-
2梅俪凡,李碧霜,吴海珍.腹膜透析患者胎球蛋白A和C反应蛋白与患者心血管事件发生的相关性研究[J].现代医学,2015,43(1):79-82. 被引量:7
-
3丁守坤,杨朝宽,李永强,王丽霞.超声测定老年人颈动脉内膜-中膜厚度的预测价值[J].中国老年学杂志,2011,31(8):1310-1312. 被引量:5
-
4颜伟健,胡杨青,王兴健,李君科,钟春花,罗丽叶.血液透析患者留置临时导管对血管的继发改变[J].实用医学杂志,2016,32(20):3333-3334. 被引量:3
-
5O'leary DH,蔡跃增.高分辨颈动脉超声:过去、现在和将来[J].国外医学(临床放射学分册),1990,13(6):332-334.
-
6侯健,孙建良.胆道手术患者全麻复合硬膜外阻滞对血糖的影响[J].苏州医学院学报,2000,20(7):675-675.
-
7文萍,王珍丽,宋薇薇,舒莉.彩色多普勒超声检测高血压病病人动脉变化的意义[J].人民军医,2005,48(10):571-572. 被引量:1
-
8龚立峰,卢景奎,马桂香,唐卫刚,许敏.桡动脉中膜内膜厚度比值在监测慢性肾脏病5期患者血管钙化中的意义[J].临床肾脏病杂志,2012,12(6):256-258.
-
9宋英姿,张云革.彩超在颈动脉硬化及冠心病诊断中的临床价值探讨[J].中国冶金工业医学杂志,2006,23(5):594-595. 被引量:1
-
10张菲菲,张雪晶,柴建,高延霞.维持性血液透析患者血清Fetuin-A、炎症因子水平与心脏瓣膜钙化的相关性[J].山东医药,2015,55(6):37-39. 被引量:1