摘要
目的：探讨老年糖尿病人事件相关电位的改变。方法：应用听觉ｏｄｄｂａｌ序列刺激的事件相关电位方法对老年糖尿病人（Ⅱ型）３０例（病人组），健康老年人２０人（对照组）进行比较。结果：病人组较对照组Ｐ３波潜伏期延长，波幅降低，经统计学处理有显著性差异（Ｐ＜０．０５）。病人组脑ＣＴ检查证实中枢神经系统存在病变（脑萎缩与腔隙性脑梗塞）者，其Ｐ３波潜伏期延长与波幅降低显著。结论：脑ＣＴ和脑事件相关电位检测对老年糖尿病合并中枢神经病变程度的了解。
Objectives:To explore the changes of eventrelated potentials (ERP)in old patients with insulin independent diabetes mellitus.Methods:Auditory eventrelated potentials were recorded in 20 normal health (control group )and in 30 old patients with insulin independent diabetes mellitus (patients group).Results:Reduced amplitude and delayed latency of ERPs were found.There were a significance difference (P<0.05) between control group and patients group.Brain CT was performed in patients group and found that there were disorders of central nervous system (such as brain atrophy and lacuna infarction).Conclusions:ERPs and brain CT may play a significant role in the treatment and finding disorders of central nervous system in old patients with insulin independent diabetes mellitus.
