泌尿生殖道支原体感染的特征及耐药分析

Isolated Rate and Drug Resistance of Mycoplasma from Genitourinary Tract

目的了解泌尿生殖道支原体的感染情况及耐药现状，指导临床合理用药。方法支原体的鉴定和药敏采用珠海黑马生物工程公司的支原体鉴定药物选择测试卡。结果在1103份标本中，418份检出支原体，阳性率为37．9％；解脲脲支原体感染的268例，人支原体感染的13例，解脲脲支原体和人支原体混合感染的137例；支原体感染以中青年为主（20-45岁），占阳性患者的80．1％，对支原体敏感的药物以次为多西环素、米诺环素、四环素、交沙霉素、克拉霉素等。结论支原体是泌尿道感染的常见病原体，应重视支原体的感染及其耐药性的变迁，为临床医生用药提供参考。

OBJECTIVE To investigate the characteristics of mycoplasma infection and antifungal resistance to guide the clinical reasonable usage. METHODS Mycoplasma was isolated and its antibiotic susceptibility was detected by Mycoplasma IES test kit. RESULTS Among the 1103 samples, 418 （37.8%） were positive, including 268 with Ureaplasma urealyticum （Uu） （64. 1%）, 13 with Mycoplasma horninis （Mh） （3. 1%）, and 137 with mixed infection （Uu and Mh） （32.8%）, Young people with the age from 20 to 45 were the highest group of infection （80. 1%）, Sensitive antibiotics to mycoplasma in precedence order were doxycyline, minocycline, tetracycline, josamycin, and clarythromycin. CONCLUSIONS Mycoplasma is a common pathogen resulting in urogenital tract infection. We should pay more attention to monitor mycoplasma infection and use antibiotics properly and to guide clinically antibiotics usage.