黄牛木中的异戊烯基酮类化合物

A new xanthone from Cratoxylum cochinchinense

目的研究黄牛木茎60%乙醇提取物的化学成分。方法运用多种色谱学方法对黄牛木茎60%乙醇提取物的化学成分进行分离,并根据光谱数据鉴定化合物的结构。结果从该植物中分离得到5个酮类化合物,分别鉴定为1,7-二羟基-2-(3-甲基丁-2-烯基)-5″-羟基-6″-甲基-6-″(4-甲基戊-3-烯基)-4″,5″-二氢吡喃(2″,3″:3,4)双苯吡酮(Ⅰ)、5,9-二羟基-8-甲氧基-2,2-二甲基-7-(3-甲基丁-2-烯基)-2H,6H-吡喃-[3,2-b]-双苯吡-6-酮(Ⅱ)、黄牛木酮A(Ⅲ)、4-(3′,7′-二甲基辛-2′,6′-二烯基)-1,3,5-三羟基-9H-双苯吡-9-酮(Ⅳ)和黄牛木酮A(Ⅴ)。结论化合物Ⅰ为新化合物,命名为越南黄牛木酮E(cracochinchinone E)。化合物Ⅱ和Ⅳ为首次从黄牛木属植物中分离得到。

Objective To study the chemical constituents from 60% ethanol extract of the stems in Cratoxylurn cochinchinense. Methods Compounds were isolated through various chromatographic methods and identified by spectroscopic data. Results Five xanthones were obtained. Their structures were characterized as 1, 7-dihydro xy-2- （3-methylbut-2-enyl）-5＂-hydroxy-6＂-met hyl-6＂- （4-methylpent-3-enyl）-4＂, 5＂-dihydropyrano （2＂, 3＂： 3, 4） xanthone （Ⅰ）, 5, 9-dihydroxy-8-methoxy-2, 2-dimethyl-7-（3-methylbut- 2-enyl）-2H, 6H-pyrano-[3, 2-b]-xanthen-6-one （Ⅱ）, cratoxylumxanthone A （Ⅲ）, 4-（3＇, 7＇-dimethylocta-2＇, 6＇-dienyl）-1, 3, 5-trihydroxy-9H-xanthen-9-one （Ⅳ）, and cochinchinone A （Ⅴ）. Conclusion Compound Ⅰ is a new compound, named cracochinchinone E. Compounds Ⅱ and Ⅳ are reported for the first time from the plants of Cratoxylum Bl.