尿激酶溶栓治疗高海拔地区急性心肌梗塞疗效观察

EFFECTS OF UROKINASE ON ACUTE MYOCARDIAL INFARCTION AT HIGH ALTITUDE

目的：本文旨在对高海拔地区（西宁，海拔2262m）应用国产尿激酶治疗急性心肌梗塞临床疗效作初步探讨;方法：共选择我院1992年10月～1996年10月收治AMI患者76例。其中33例接受尿激酶静脉溶栓治疗，与非溶栓组对比观察：结果：①溶栓组梗塞相关血管再通率66.67％.显著高于非溶栓组（23.20％，P＜0.01）;②4周病死率：溶栓组低于非溶栓组11.84个百分点;③溶栓组不良反应发生率为12.12％，无脑出血;结论:我们认为高原地区应用国产尿激酶溶栓治疗AMI是有效、安全的。

To explore a therapitical effects of urokinasc on acute myocardial infarction in Xining (2260m above sea level). Methods: 76 cases with AMI,data coming from our hospital on oct.1992 to oct. 1996, were divided into two groups, thromblytic group and control group. The former was administed urokinase, iv. Results: The relating reperfusion rate and mortality was 66.67% and 9.09% in thromblytic group,23.20% and 20.93% in control. The reperfusion rate had a significant difference (P<0.01 ) between two groups. Conclusions: Effects of urokinase on AMI is clinically safety and active at high altitude.