穴位注射黄芪、丹参注射液治疗慢性疲劳综合征的临床研究

Clinical research of chronic fatigue syndrome treated by injecting Astragalus root and Danshen root in the acupoints BL18,BL20 and BL23

目的观察肝俞、脾俞和肾俞穴位注射黄芪、丹参注射液治疗慢性疲劳综合征的临床疗效。方法将180例慢性疲劳综合征患者随机分为2组。治疗组92例应用双侧肝俞、脾俞和肾俞穴位注射黄芪、丹参注射液2mL治疗,对照组88例应用双侧足三里、手三里和丰隆穴位注射黄芪、丹参注射液2mL治疗,黄芪、丹参注射液5:1配伍,隔日(或2d)1次,10次为1个疗程。应用疲劳量表(FS)、疲劳评定量表(FAI)、抑郁自评量表(SDS)、焦虑自评量表(SAS)和生活质量综合评定问卷(GOLI)对患者治疗前、后进行客观评价。结果2组治疗后FS、FAI、SDS、SAS和GOLI评分与本组治疗前比较均有统计学意义(P<0.05);治疗后2组FS、FAI、SDS、SAS和GOLI评分比较均有统计学意义(P<0.05)。结论肝俞、脾俞和肾俞穴位注射黄芪、丹参注射液治疗慢性疲劳综合征安全、有效、经济和方便。

Objective To investigate the pathogenesis and find a safe, effective, economic, convenient therapy for chronic fatigue syndrome （CFS）. Methods 180 patients with CFS are randomly divided into treatment group in which 92 patients will be treated by injecting Astragulus mot and Danshen Root in bilateral acupoints BL18, BL20 and BL23 and control group in which 88 patients will be treated by injecting Astragalus Root and Danshen Root in bilateral aeupaints ST36, LI10 and ST40. Then objectively evaluate the inventories of IS, FAI, SDS, SAS and GOLI before and after treatment. Results Indexes of FS, FAI, SDS, SAS and GOLI after treatment were superior to those before treatment （ P 〈 0.05） in two groups. There were significant differences between two groups on indexes of FS, FAI, SDS, SAS and GOLI after treatment （ P 〈 0.05）. Condusion The pathogenesis of CFS is the disfunction of liver, spleen and kidney. Disease is mainly in liver, spleen and kidney .The injection of Astragalus mot and Danshen Root in the acupoints BL18, BL20 and BL23 is a safe, effective, economic, convenient therapy for CFS.