清咽雾化液治疗慢性咽炎56例

The Clinical Study of Chinese Herbal Qingyan Vaporous Atomization Treating Chronic Pharyngitis

目的观察清咽雾化液的临床疗效,探讨其作用机制。方法慢性咽炎患者97例,分为治疗组56例,对照组41例,分别采用清咽雾化液和西药制剂行超声雾化治疗,12 d后观察疗效;并取咽部黏膜组织,在电镜和光镜下观察治疗组治疗前后组织学及超微结构变化。结果治疗组和对照组临床总有效率分别为92.86%,75.60%(P<0.05);组织学上表现为治疗后咽后壁黏膜炎性细胞浸润减少,细胞质中的空泡结构基本消失,核膜轮廓渐趋清晰,腺体分泌颗粒减少。结论清咽雾化液超声雾化治疗慢性咽炎能有效减轻局部黏膜的炎性反应状态,修复受损上皮细胞,减轻患者症状。

Objective To investigate the therapeutic effects of Chinese herbal qingyan vaporous atomization on chronic pharyngitis. Methods 97 patients with chronic pharyngitis were divided into two groups： research group treated with qingyian ultrasonic steam inhalation and the other group treated with traditional western medicine steam inhalation. Changes in the main symptoms and signs were comparatively observed before and after the therapy in 2 groups. Then the pharynx mucosal tissues biopsies were detected using light and electron microscope before and after therapy. Results The total effective rates for chronic pharyngitis were 92.86% and 75.60% respectively in Chinese and western medicine ultrasonic steam inhalation groups （P 〈 0.05 ）. The histological observation revealed that after Chinese herbal qingyan therapy, the number of inflammation infiltration cells deceased, the contour of nuclear membrane became clear, and the secretion of glandular organ reduced. Conclusion The Chinese herbal qingyan ultrasonic steam inhalation therapy is an effective therapeutics for the treatment of chronic pharyngitis through significantly inhibiting the inflammation condition of local mucosal tissue .