急性冠脉综合征患者白细胞计数与病情的关系探讨

Study on the relationship between white blood cell count and pathogenetic condition in acute coronary syndrome

目的初步探讨急性冠脉综合征(ACS)患者白细胞计数(WBC)与病情的关系。方法ACS患者80例,分为不稳定型心绞痛(UA,n=38)组和急性心肌梗死(AMI,n=42)组,另按Gensini评分(Score)将80例患者分为<30及≥30组。比较各组的WBC变化并分析WBC与CK-MB、TnT、BNP、Score值的关系。结果AMI组WBC及CKMB、TnT、BNP、Score值均显著高于UA组(P<0.05-0.01);Score≥30分组的WBC显著高于Score<30分组(P<0.05);WBC与Score、TnT、CKMB、BNP均呈显著正相关(r=0.289-0.344,均P<0.01)。结论ACS患者WBC升高与病情严重程度有一定关系。

Objective To study the relationship between white blood cell count （WBC） and patho- genetic condition in acute coronary syndrome （ACS）. Methods Eighty patients with ACS were divided into two groups, which were unstable angina （UA, n= 38） group and acute myocardium infarction （AMI, n=42） group. At the same time, according to 〈30,〉30 of Gensini system （Score）, 80 cases were divided into two groups. The value of WBC of each group was compared and the relationship be- tween WBC and CKMB, TnT, BNP, Score was analyzed. Results CKMB, TnT, BNP, Score and WBC of AMI group was significantly increased than that of UA group （P〈0. 05-0. 01）, the WBC of Score ≥30 group was significantly more than of Score〈30 groups （P〈0. 001）, and there was significant positive correlation between WBC and Score, TnT, CKMB, BNP （r=0. 289--0. 344, all P（0. 01）. Conclusion There was the specified relationship between WBC and the grave degree of pathogenetic condition in the patients with ACS.