小剂量ALG在肾移植术后的预防性应用

The preventive use of low dose ALG in renal transplantation

目的探讨小剂量抗淋巴细胞球蛋白(ALG)在肾移植术后预防性应用的临床价值。方法回顾性分析肾移植术后预防性应用小剂量ALG的临床资料。结果本组47例患者肾移植术后肾功能全部恢复正常,仅1例发生急性排斥反应,无严重感染发生。结论肾移植术后预防性应用小剂量ALG,不仅可减少移植肾急性排斥反应发生率,而且可尽量降低严重感染发生的风险。

Objective To investigate the clinical effect of the preventive use of low anti-lymphocyte globulin （ALG） in renal transplantation. Methods 47 cases were retrospectively analyzed. Results The renal functions of 47 cases were all recovered. There was not any serious infection, but one case with acute rejection. Conclusion The preventive use of low dose ALG was efficient to reduce the incidence of acute rejection and risk of serious infection.