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Toll样受体与造血 被引量：1

Toll-like receptor and haemopoiesis
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摘要 Toll样受体（TLR）是近年来发现的一类天然免疫受体，在天然免疫及获得性免疫过程中均发挥非常重要的作用。对TLR的深入研究表明，TLRs在造血相关细胞（造血干／祖细胞、间充质干细胞、血管内皮细胞等）上均有不同程度的表达，并且发挥一定生物学效应。 Toll-like receptor is a kind of innate immunity receptor found in recent years. It plays an important role in innate immunity and adaptive immunity. Further researches indicate that TLRs are expressed on various kinds of hematopoietic cells including haemopoietic stem/progenitor cells, mecenchymal stem cells and vascular endothelial cells and play biological effect. Here we review the expression of TLR on hematopoietic cells and its role on haematopoiesis.
作者 陈欣 王兴兵 孙自敏
机构地区 安徽医科大学附属省立医院血液科
出处 《国际免疫学杂志》 CAS 北大核心 2009年第2期132-135,共4页 International Journal of Immunology
基金 国家自然科学基金项目（30700329） 安徽省第四批优秀青年科技基金项目（08040106810） 安徽省自然科学基金（06013128B） 安徽省教育厅课题（2006KJ072C）
关键词 TOLL样受体 造血 造血细胞 Toil-like receptor Hematopoiesis Hematopoietic cell
分类号 R392.1 [医药卫生—免疫学]
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参考文献20

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同被引文献18

  • 1侯春丽,朱楚洪,应大君.外源性A20基因对缺氧诱导的内皮细胞E-选择素表达的影响[J].解剖学杂志,2007,30(1):1-3. 被引量：1
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国际免疫学杂志
2009年 第2期

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