电阻抗监护小猪腹膜后注血模型的研究

Experimental study on electrical impedance tomography for monitoring retroperitoneal inject blood model in pigs

目的使用小猪腹膜后注血模型来研究电阻抗成像监测创伤导致的腹膜后出血的可行性，为电阻抗成像的临床应用提供必要的理论和现实依据。方法5头小猪行腹膜后穿刺置管，经导管持续注入血液，模拟创伤性腹膜后出血，应用电阻抗成像监测小猪注血部位的阻抗和图像变化情况。结果5头腹膜后注血小猪电阻抗监护图像成像清晰，稳定。注血部位的阻抗值随注血量的增加而持续降低，图像灰度变化明显。经CT及解剖验证，后腹膜完整，血液局限于腹膜后间隙内。结论在小猪腹膜后注血模型的基础上，使用电阻抗监护腹膜后出血成像清晰，对比明显。

Objective To apply electrical impedance tomography that is a new evaluation approach to monitor the development of retroperitoneal injury. We used retroperitoneal inject blood model in pigs to study the feasibility on monitoring retroperitoneal bleeding and to provide premise in theory and practice for clinical application. Methods Five pigs were used on the experiment. We insert a vessel into the retroperitoneal and inject blood to simulate retroperitoneal bleeding. Sixteen electrodes were attached on the abdominal region circumference of pigs and used for electrical current injection and surface voltage measurement. Then the monitoring images were performed by electrical impedance tomography. Results The images of electrical impedance tomography retroperitoneal inject blood model of five pigs were clear, the minimal impedance scale was decreasing significantly as the bleeding volume increasing and the images were changed significantly too. The computerized tomography and the dissecting results confirmed the blood was limited in retroperitoneal. Conclusions The establishments of pigs retroper- itoneal inject blood model was successful. The images of electrical impedance tomography retroperitoneal inject blood model were clear with significant contrast. It＇s feasible to use electrical impedance tomography system to monitor the retroperitoneal bleeding. This technique may become a useful tool for monitoring retroperitoneal injury in intensive care patients.