64层螺旋CT冠状动脉成像对冠状动脉粥样硬化病变的诊断准确性评价

Accuracy of 64-slice Multi-detector Row CT Angiography in the Diagnosis of Coronary Artery Lesions

目的探讨64层螺旋CT冠状动脉成像（CTA）对冠状动脉粥样硬化病变的诊断价值。方法收集2006年7月至2007年5月在我院行64层螺旋CTA和传统冠状动脉造影（SCA）的49例患者的影像资料，以SCA作对照，评估64层螺旋CTA诊断冠状动脉狭窄性病变的准确性。结果其中46例图像（93．88％，46／49）达到诊断标准，64层螺旋CTA诊断冠状动脉〈50％、50％～75％、≥75％狭窄性病变敏感性分别为54．88％、47．50％、93．15％，特异性分别为99．42％、95．68％、97．13％。64层螺旋CTA和SCA对冠状动脉狭窄的量化分析具有明显的相关性（r=0．941，P〈0．01）。结论64层螺旋CTA是评价冠状动脉粥样硬化病变的一种较好的检查方法。

Objective To determine the accuracy of 64-slice computed tomography angiography （CTA） in the diagnosis of coronary artery lesions. Methods We retrospectively collected the coronary artery imaging data of 49 patients who underwent 64-slice CTA and conventional catheter-based selective coronary angiography （SCA） during July 2006 and May 2007. The CTA and SCA diagnosis were compared. Results The 64-slice CTA enabled the visualization of the entire coronary tree with diagnostic image quality in 46 of the 49 patients. The CTA had a sensitivity of 54.88%, 47.50% and 93.15%, and a specificity of 99.42%, 95.68% and 97.13% for detecting less than 50% stenosis, 50%-75% stenosis, and greater than 75% stenosis, respectively. The overall Pearson＇s correlation coefficient between the degree of stenosis detected by quantitative SCA and 64-slice CTA was 0. 941. Conclusion 64-slice CTA is a good instrument for assessing coronary artery lesions.