结肠透析与常规灌肠治疗肝性脑病的临床观察

Clinical observation on colon dialysis and routine enema to treat patients with hepatic encephalopathy

[目的]探讨结肠透析与常规灌肠治疗肝性脑病的效果。[方法]60例肝性脑病病人随机分为两组,对照组28例,观察组32例,两组均给予基础的保肝、抗肝性脑病等综合治疗,对照组给予常规乳果糖灌肠液保留灌肠,观察组采用在结肠灌洗透析后予乳果糖灌肠液保留灌肠。观察并比较两组治疗后平均清醒时间、治疗效果、治疗前后血氨值及灌肠液在肠腔内保留时间。[结果]观察组平均清醒时间短于对照组;观察组总有效率为96.87%,对照组总有效率为85.71%,观察组明显优于对照组(P<0.05);两组治疗后血氨值明显降低;观察组灌肠液在肠腔内保留时间延长。[结论]在综合治疗的基础上,结肠灌洗透析后给予乳果糖联合氧氟沙星保留灌肠治疗肝性脑病效果满意。

Objective:To probe into the effect of colon dialysis and routine enema to treat patients with hepatic encephalopathy.Methods:A total of 60 hepatic encephalopathy patients were randomly divided into control group(28 cases) and test group(32 cases).All cases were given basic comprehensive therapy including liver protection and anti-hepatic encephalopathy.And routine retention enema with lactulose fluid was given as retention enema for control group cases,whereas observation group cases accepted retention enema with lactulose fluid after coloclysis dialysis.Then the average conscious time,curative effect,blood ammonia value before and after treatment and keeping time of enema fluids in enteric cavity of all cases were observed and compared.Results:The average conscious time of test group patients was shorter than that of control group cases.The total effective rate was 96.87% in test group and 85.71% in control group.There was statistical significant difference between them(P<0.05).The blood ammonia value after intervention in both groups decreased significantly.The keeping time of enema fluid in enteric cavity was prolonged in test group cases.Conclusion:Based on comprehensive therapy,lactulose in combination with ofloxacin retention enema after colon coloclysis dialysis for hepatic encephalopathy patients could gain satisfied curative effect.