月经失调女运动员代谢状态的研究

Metabolic Study of Female Athlete with Menstrual Disturbance

目的:通过对激素内分泌和相关底物的监控,分析不同月经失调形式的激素紊乱状况和相关底物的水平,探讨较轻形式的月经失调(黄体功能失调和无排卵)是否处于一种节约能量的低代谢状态;方法:受试者为30名专业女运动员和8名无运动训练经历的女青年,检测其月经周期状况,并分为照排卵周期组、运动排卵周期组、运动LPD周期组和运动无排卵周期组,收集尿液和取血,检测相关激素的底物的水平;结果:运动LPD周期组和运动无排卵周期组血清总T3水平降低(P<0.05),胰岛素水平降低(P<0.05),瘦素水平降低(P<0.05),皮质醇水平升高(P<0.01),生长激素、IGF-I、IGFBP-3没有改变,胃饥饿素水平没有改变,空腹血糖水平没有变化;结论:LPD运动女性和运动无排卵女性总T3降低,瘦素水平降低,胰岛素水平降低,这提示这些运动女性处于一种低代谢状态,但程度轻于闭经运动员。

Objective： By monitoring endocrine hormones and substrates, hormone disturbance and substrates level were analyzed and whether or not female athletes were in a hopometabolic state were explored. Method：The participators were 30 professional female athletes and 8 sedentary female. After 2 menstrual cycle＇s observation, all cycles were classified as 4 groups （SedOvul, ExeOvul, ExeLPD, ExeAnov）, and urine and blood were collected to analyze hormones and substrates. Result ： The T3 , insulin, leptin levels of LPD and anovulatory cycles were decreased（P〈0.05）, the cortisol level of LPD and anovulatory cycles was increased（P〈0. 01）, the hGH, IGF-I, IFGBP-3 of LPD and anovulatory cyeles had no change, and the Ghrelin, fasting blood glucose levels of LPD and anovulatory cycles had no changes. Conclusion ： In LPD and anovulatory cyeles, blood T3 , leptin, insulin level was declined and cortisol level was increased, which indicated that exercise females were in a hypometabolic state.