良性阵发性位置性眩晕的发病因素

Pathogenesis of Benign Paroxysmal Positional Vertigo

目的探讨良性阵发性位置性眩晕(BPPV)的发病因素。方法回顾性分析145例BPPV患者的年龄、性别对BPPV发病的影响,并探讨BPPV发病与内耳缺血之间的关系。结果男性BPPV患者的高刺激听性脑干反应(ABR)的异常率为22.1%(32/145)、女性为37.2%(54/145);中年(30～55岁)BPPV患者的高刺激ABR的异常率为37.9%(55/145)、老年(>55岁)BPPV患者为21.4%(31/145);不同性别、年龄BPPV患者高刺激率ABR异常率差异无显著性(P>0.05)。结论内耳缺血可能与BPPV发病有关,但BPPV发病在不同性别、年龄之间差异无显著性。

Objective To explore the etiological factors of benign paroxysmal positional vertigo （ BPPV）. Methods The clinical data of 145 patients with BPPV were retrospectively reviewed. The impacts of gender and age on BPPV were analyzed. The relationship between the onset of BPPV and the internal ear ischemia was also explored. Results The abnormality rate of auditory brainstem response （ABR） under high stimulus rate was 59. 3% （86/145） in all the patients with, including 22. 1% （32/145） in male and 37.2% （54/ 145） in female （P 〉0. 05）. The abnormality rate of ABR under high stimulus rate were 37.9% （55/145） and 21.4% （31/145） in middle-aged （30-55 years） and old （ 〉 55 years） patients, respectively （P 〉 0. 05）. Conclusion The onset of BPPV may relate to ischemic internal ear but is not relevant with gender and age.