胃印戒细胞癌对T、N、M分期的影响

Effect of gastric signet ring cell cancer on T, N, M stages

目的探讨胃印戒细胞癌对T．N、M分期的影响，评估胃印戒细胞癌的T、N、M分期是否与管状腺癌有差异。方法对351例接受≥D2胃切除术的胃癌患者进行回顾性分析，单因素分析59例组织学类型为印戒细胞癌和161例为管状腺癌的T、N、M分期的差异；多因素分析印戒细胞癌对T、N、M分期的影响。结果卡方检验提示胃印戒细胞癌与管状腺癌的T、N、M分期没有差异。多因素分析发现印戒细胞癌不是影响T、N、M分期的独立影响因素。结论胃印戒细胞癌的T、N、M分期与管状腺癌的比较无统计学意义。

Objective To evaluate the effect of the gastric signet ring cell cancer （SIG） on the T, N,M stages. Methods Three hundred and fifty-one patients undergoing D2 or greater gastrectomy for gastric cancer were analyzed retrospectively. The T, N, M stages of 59 patients with SIG and 161 patients with tubular adenocarcmoma （TUB） were compared using univariate and multivariate analysis. Results The chi-square test showed that there were not significant differences in T, N, M stages between TUB and SIG. Multivariate Logistic regression analysis indicated that SIG was not a independent factor influencing the T, N, M stage. Conclusion Gastric cancer with SIG has not higher T,N,M stages than that with TUB.