中国人肝动脉化疗栓塞死亡原因分析（14年病例统计）

Cause of death after TACE in China during the past 14 years

目的探讨中国人近14年肝动脉化疗栓塞（TACE）的死亡原因和发病基础。方法联合检索中国生物医学文献数据库和中国知识资源总库1994年01月-2008年09月的相关文章，分析TACE术后死亡的原因、特点。结果中国近14年共报道150例TACE术后病死病例，其中肝功能衰竭、上消化管出血和肝癌破裂出血约占84％，78．7％的病死病例发生在TACE术后1月内。结论肝功能衰竭、上消化管出血和肝癌破裂出血是TACE术后主要的致死性并发症，且所有的病死病例中绝大多数是早期死亡。

Objective To study the cause of death and mechanism after （TACE） in China during the past 14 years. Methods Related reports in Chinese Medical Current Content （CBM） and National Knowledge Infrastructure （CNKI） from January 1994 to June 2008 were retrieved. The cause of death and mechainsm after TACE were analyzed. Results A total of 150 patients who died after TACE were reported in China during the past 14 years. 84% cases were caused by liver function failure, upper gastrointestinal bleeding and rupture of liver cancer, 78.7% cases died one month postoperation. Conclusion Liver function failure, upper gastrointestinal bleeding and rupture of liver cancer are the main complications which can cause death and the majority cases died early.