校正Q-T间期在糖尿病心脏自主神经病变中的诊断价值

Diagnostic Value of Corrected QT Interval in Diabetic Patients with Cardiac Autonomic Neuropathy

目的探讨校正Q-T间期(QTc)在糖尿病患者心脏自主神经病变(CAN)中的诊断价值。方法采用Ewing法对147例糖尿病患者进行心脏自主神经功能检查并据此分为CAN组及非CAN组,比较两组间QTc的差异,同时分析QTc与CAN病变程度之间的相关性。结果CAN组的QTc([429±22)ms]与非CAN组([397±14)ms]相比显著延长,且QTc与CAN病变程度之间呈正相关。结论QTc在诊断糖尿病CAN中具有重要的参考价值。

Objective To investigate the diagnostic value of corrected QT interval in diabetic patients with cardiac autonomic neuropathy. Methods We studied 147 diabetic patients with Ewing＇s methodology and divided them into CAN group and non-CAN group,then compared the difference of QTc and analyzed the relationship between QTc and the severity of CAN. Results The QTc of CAN group [（429 ± 22） ms] was significantly prolonger than that of non-CAN group[（397 ±14）ms], moreover the QTc interval was positively correlated with the severity of CAN. Conclusion The QTc interval has considerable reference value in the diagnosis of diabetic CAN.