非酒精性脂肪肝患者肝酶与代谢综合征的关系

Association of Abnormality of Liver Enzymes and Metabolic Syndrome in Patients with Non-alcohoblic Fatty Liver Disease

目的分析非酒精性脂肪肝病患者中肝酶与代谢综合征的关系。方法收集山西某电厂体检发现的NAFLD患者144例,测量身高、体重、腰臀围,检测丙氨酸转氨酶,血脂,空腹血糖。结果该人群中MS患病比例为39.58%,肝酶异常者52例占36.11%,其中MS中57例肝酶异常比例达48.08%。MS组肝酶高于非MS组。结论30%以上NAFLD患者存在肝酶异常,肝酶异常者中MS检出率明显增高。

Objective To investigate the changes of liver enzymes in the patients with non-alcoholic fatty liver disease and to analyze the association between liver enzymes and metabolic syndrome. Methods 144 patients with NAFLD underwent anthropometry,laboratory tests included alanine aminotransferase,serum lipid,fasting plasma glucose,and abdominal ultrasonography. Results 52 of the 144 NAFLD patients showed that have abnormal liver enzymes. 57 of the 144 NAFLD patients were diagnosed as with MS. 48.08%of those with abnormal liver enzymes were diagnosed as with MS, a percentage significantly higher than that of those without normal liver enzyme（P〈 0.05 ）. The levels of the liver enzymes was higher in the group with MS than in the group without MS （P〈 0.05）. Conclusion Most patients with NAFLD have abnormal liver enzymes, and the percentage of MS is higher in the abnormal liver enzyme group.