无创正压通气对慢性阻塞性肺疾病患者肺功能的影响

The effect of non-invasive positive pressure ventilation on pulmonary function of patients with chronic obstructive pulmonary disease(COPD)

目的探讨无创正压通气(NIPPV)对慢性阻塞性肺疾病(COPD)患者近期肺功能的影响。方法对42例因COPD急性加重(AECOPD)住院治疗的患者随机分成两组,一组采用常规方法治疗,另一组在常规治疗的基础上加用NIPPV治疗。观察两组患者FEV1、FVC的变化及住院时间。结果经1周的治疗,NIPPV组较非NIPPV组改善程度更大。NIPPV组住院时间更短。两组之间的差异存在统计学差异(P<0.05)。结论无创正压通气能够促进AECOPD患者肺功能的恢复,同时能够缩短AECOPD患者的住院时间。

Objective To investigate the effect of non-invasive positive pressure ventilation on pulmonary function in the near future of patients who suffered from chronic obstructive pulmonary disease（COPD）.Methods A total of 42 patients due to acute exacerbation of COPD（AECOPD）were randomly divided into conventional therapy group and NIPPV group（NIPPV plus conventional therapy）.The change of FEV1,FVC and duration of hospitalization were observed.Results FEV1,FVC were significantly higher in NIPPV group than in conventional therapy group after one week＇s treatment（P〈0.05）.And length of hospital stay was decreased in NIPPV group compared with conventional therapy group（P〈0.05）.Conclusion NIPPV can promote recovery of pulmonary function of patients with AECOPD,and also can short length of hospital stay of these patients.