老年男性高尿酸血症患者心血管危险因素分析

A Study on Cardiovascular Risk Factors for Hyperuricemia in the Male Elderly

目的探讨老年男性患者高尿酸血症的患病率及其心血管危险因素。方法对健康查体的老年男性患者进行血压、身高、体质量、腰围、臀围、血清肌酐、总胆固醇、低密度脂蛋白胆固醇、甘油三酯、血清尿酸、血糖测定;并探讨影响高尿酸血症发生的心血管危险因素。结果1677例老年男性患者血尿酸水平(349.29±87.60)μmol/L,其中高尿酸血症者372例占22.18%。在高尿酸血症患者中肥胖、肾功能不全、高脂血症、高血压的发生率显著高于血尿酸正常者,差异有统计学意义。结论高尿酸血症在老年男性患者中占相当的比例。高尿酸血症与高血压、腹型肥胖、高甘油三酯血症、肾功能损害等心血管危险因素密切相关。

Objective To explore the prevalence of hyperuricemia in the male elderly and the various cardiovascular risk factors for it. Methods The cross-sectional study was based on an male elderly population that was given health examination in our hospital, whose blood pressure, body weight, height, waist circumference, hip circumference, fasting serum creatinine, total cholesterol, low-density lipoprotein cholesterd, serum triglyceride, blood sugar and serum uric acid were measured or determined. BMI（body mass index）, waist-to-hip ratio and clearance of creatinine（Ccr） were calculated. Results The average level of serum uric acid of the 1677 subjects was （349.29±87.60）μmol/L, among whom there were 372 cases of hyperuricemia , accounting for 22.18%. The prevalence of hypertension, obesity, hypertriglyceridemia and impaired renal function was higher of hyperuricemia than the normal group, with the differences being statistically significant. Conclusion The prevalence of hyperuricemia in the elderly male population is on the high end; hyperuricemia is closely associated with varios factors such as high blood pressure, visceral obesity, high serum tryglyceride, impaired renal function.