摘要
葛根素(puerarin)是从中药葛根中提取的主要有效成分之一,为一种异黄酮化合物。它具有抑制脑细胞凋亡,保护神经细胞的能力,还能够提高神经元抵抗损伤的能力,可用于治疗脑损伤以及神经退行性疾病。本文就葛根素对中枢神经系统神经细胞的保护作用及机制方面的研究进展做一综述。
Puerarin is one of the major isoflavonoid compounds isolated from Radix Puerariae, which has been used in traditional Chinese medicine for centuries. The compound was found to inhibit neuronal apoptosis, protect nerve cells against hypoxic/ischemic injuries. Thus, puerarin may be used to treat brain traumas and neurodegenerative diseases. This article reviews the recent progress in research on neuroprotective effects of puerarin and the related mechanisms.
出处
《生命科学》
CSCD
北大核心
2009年第1期131-134,共4页
Chinese Bulletin of Life Sciences
基金
陕西师范大学留学回国人员科研启动基金(999195)
关键词
葛根素
神经细胞
保护作用
puerarin
neural cells
protective effect
