聚合有机凝胶印迹膜对D-和L-苯丙氨酸的选择性吸附

Selective Adsorption of D- and L-Phenylalanine on the Imprinted Polymerized Organogel Membranes

以1-甲基-2,4-二(N'-十八烷脲基)苯为凝胶剂,以液体单体丙烯酸-2-乙基己酯、甲基丙烯酸甲酯、二甲基丙烯酸聚乙二醇(200)酯以及模板分子和光敏引发剂的混合物为溶剂,其目的是利用该凝胶剂可在这个混合物中进行超分子自组装,形成互相缠绕的具有纳米尺寸的纤维状聚集体,并最终导致这些单体混合物形成稳定的超分子有机凝胶.然后经UV光引发聚合,经乙醇抽提凝胶剂聚集体和模板分子,制备了一种新型分子印迹的聚合有机凝胶膜材料.探讨了不同凝胶剂浓度、模板分子浓度、单体混合物配比所制备的印迹聚合有机凝胶膜对D-和L-苯丙氨酸吸附效率的影响.结果表明所制备的印迹聚合有机凝胶膜对L-苯丙氨酸吸附效率约为对D-苯丙氨酸吸附效率的3～4倍,表现出明显的选择性吸附性.

1-Methyl-2,4-bis（N′-n-octadecylureido）benzene （MBB） was used as a gelator. A mixture of 2-ethylhexyl acrylates （EHA）, methyl methacrylate （MMA） and polyethylene glycol dimethacrylates （PEG200DMA） was used as solvent in the presence of template and initiator. MBB can self-assemble in this solvent mixture to form entangled nano-sized fibrillar aggregates, ultimately turn the solvent mixture into stable supramolecular organogels. After polymerization by UV initiation and removal of MBB aggregates and template by ethanol extraction, a novel imprinted polymerized organogel membranes was obtained for the absorption of D- and L-phenylalanine. The effects of MBB concentrations, template concentrations and mass ratio of monomers on the adsorption efficiencies were investigated. The results indicate that the adsorption efficiencies for L-phenylalanine were 3 -4 times higher than that for D-phenylalanine, exhibiting distinct selective adsorption.