期刊文献+

乳腺癌癌前病变的治疗 被引量:6

Treatment of breast cancer and precancerous lesions
原文传递
导出
摘要 病理组织学检查是诊断癌前病变的最可靠标准。目前公认的癌前病变有:(1)小叶及导管不典型增生;(2)柱状上皮不典型增生;(3)小叶原位癌;(4)乳头状病变;(5)异常增生放射状瘢痕。治疗癌前病变的最有效方法是手术切除。但是必须权衡手术范围与外形美观之间的矛盾,既不要切除范围过大,造成不必要的组织缺失,也不要切除范围过小而留下复发隐患。导管原位癌是乳腺癌的早期阶段,但是,纯粹的导管原位癌不具有侵袭性,被看作癌前病变和癌的中间状态。手术切除、放疗加降低风险的内分泌治疗是导管原位癌主要治疗方法。 Up to now, pathological diagnosis is the final decision for precancerous lesions, and surgery is the most effective management. There is a particular dilemma for surgeons, who must balance the risk of resecting too much and causing unnecessary cosmetic damage, or resecting too small and leaving an increased risk of recurrence. Ductal carcinoma in situ(DCIS) is the intermediate stage between precancerous lesions and invasive breast carcinoma, surgery, radiotherapy and risk reduction endocrinotherapy have become the main treatment for DCIS.
出处 《中国实用外科杂志》 CSCD 北大核心 2009年第3期207-210,共4页 Chinese Journal of Practical Surgery
关键词 乳腺癌 癌前病变 breast cancer precancerous lesions
  • 相关文献

参考文献13

  • 1Arpino G, Laucirica R, Elledge RM. Premalignant and in situ breast disease: biology and clinical implications [J]. Ann Intern Med,2005,143(6):446-457.
  • 2Costa A, Zanini V. Precancerous lesions of the breast [J]. Nat Clin Pratt Oncol,2008,5(12): 700-704.
  • 3Donald L,Wiekerham. Average annual rates of invasive and noninvasive breast cancer by history of LCIS and atypical hyperplasia for participants in the BCPT. NSABP-PI ASCO, 2001:327.
  • 4Chuba PJ. Hamre MR, Yap J, el al. Bilateral risk for subsequent breast cancer after lobular carcinoma-in-silu: analysis of surveillance, epidemiology, and end results data [J]. J Clin Oncol, 2005,23 ( 24 ):5534-5541.
  • 5Anderson BO, Calhoun KE. Rosen EL. Evolving concepts in the managemenl of lobular nenplasia [J]. J Natl Compr Cane Netw, 2006.4( 5 ) :511-522.
  • 6Page DL, Salhany KE, Jensen RA, el al. Subsequent breast carcinoma risk after biopsy wilh atypia iu a breast papilloma [J]. Cancer, 1996,78 ( 2 ) :258-266.
  • 7Lewis JT, Hartmann LC, Vierkanl RA, et al. An analysis of breast cancer risk in women with single, multiple, anti atypical papilloma [J ]. Am J Surg Pathol.2006,30(6 ):665-672.
  • 8Sanders ME, Page DL, Simpson JF, et al. Interdependence of radial sear and proliferative disease with respect to invasive breasl caneinoma risk in patients with benign breast biopsies [J]. Cancer, 2006,106(7):1453-1461.
  • 9Boyages J, Delaney G, Taylor R. Predictors of local recurrence after trealment of ductal carcinoma in silu: a meta-analysis [J]. Cancer, 1999,85 ( 3 ) :616-628.
  • 10Fisher B, Dignam J, Wohnark N, et al. Tamoxifen in treatment of intraductal breasl cancer: national surgical adjuvant breast and bowel project B-24 randomised controlled trial [J].Lancet, 1999,353 (9169): 1993-2000.

同被引文献64

  • 1刘晓菲,宋爱莉,李静蔚,殷玉琨.莪术油对大鼠乳腺癌癌前病变MVD及相关调控因子VEGF/FLK表达的干预作用研究[J].中医药学报,2011,39(4):19-21. 被引量:15
  • 2王红鹰,邹强,周坚,金贻婷,劳正胤,应学翔,顾斐,任长才.乳腺癌前病变的临床诊断研究[J].外科理论与实践,2006,11(6):500-503. 被引量:3
  • 3芦锰.乳腺增生病的中医药治疗概况[J].河南中医学院学报,2007,22(2):83-85. 被引量:16
  • 4王翠平,王炳高,齐春华.乳癌诊断进展[J].青岛大学医学院学报,2007,43(4):374-376. 被引量:4
  • 5Haagensen CD, Lane N, Lattes R, et al. Lobular neoplasia so-called lobular carcinoma in situ) of the breast [J].Cancer, 1978, 42(2): 737-769.
  • 6Chuba PJ, Hamre MR, Yap J, et al. Bilateral risk for subsequent breast cancer after lobular carcinoma-in-situ: analysis of sur- veillance, epidemiology, and end results data [J]. J Clin Oncol, 2005, 23(24): 5534-554.
  • 7Robinson D, Holmberg L, Moiler H. The occurrence of invasive cancers following a diagnosis of breast carcinoma in situ [J ]. Br J Cancer, 2008, 99(4): 611-615.
  • 8Oppong BA, King TA. Recommendations for women with lobular carcinoma in situ (LC1S)[J]. Ontology (Williston Park), 2011, 25 (11): 1051-1058.
  • 9National Comprehensive Cancer Network. The NCCN Breast Cancer Clinical Practice Guidelines in Oneology(Version 1.2011) [EB/OL]. 2011 [2011-08-10J, http://www.nccn.org.
  • 10Edge SB, Byrd DR, Compton CC, et al. American Joint Commit- tee on Cancer (AJCC) Cancer Staging Manual [M]. 7th ed. New York: Springer Verlag, 2009:1-195.

引证文献6

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部