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原发性乳腺神经内分泌癌13例诊治分析 被引量：18

Diagnosis and therapy of primary neuroendocrine carcinoma of breast:an analysis of 13 cases
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摘要 目的探讨原发性乳腺神经内分泌癌的诊断和治疗策略。方法结合文献对上海市第八人民医院普外科自1980年至今收治的13例原发性乳腺神经内分泌癌的分类、流行病学、诊断和治疗方法等进行分析。结果13例中实体型原发性乳腺神经内分泌癌4例,小细胞型原发性乳腺神经内分泌癌5例,大细胞型原发性乳腺神经内分泌癌4,皆无腋窝淋巴结转移,总的5年无病存活率为76.9%(10/13),存活率为84.6%(11/13),病死率为15.4%(2/13)。结论原发性乳腺神经内分泌癌的影像学诊断比较困难,诊断上的金标准是组织活检。在治疗上,参考乳腺浸润性导管癌的治疗策略对其治疗可获得较满意效果。 Objective To discuss the strategy in diagnosis and therapy of primary neur-oendocrine carcinoma of breast. Methods The definition,classification,epidemiology,diagnose and treatment were discussed in 13 cases of primary neuroendocrine carcinoma of breast treated in surgery department of Shanghai the eighth people＇ s hospital from 1980 to now with reviewing lectures.Results In the 13 cases,4 cases was solid neuroendocrine carcinoma,5 cases was small cell neuroendocrine carcinoma,4 cases was large cell neuroendocrine carcino-ma.All of the cases＇ axillary limph node is negative.Total diseases free survival rate was 76.9% （ 10/13 ）,overal survival rage was 84.6% （11/13）.Conclusion To diagnose primary neur-oendocrine carcinoma of breast by imaging is diffficuh.The golden standard of diagnosis is biospy.It is acceptable to treat the patients with the guideline of invasive ductal carcinoma in breast.
作者 潘晓峰 毕永林 秦贤举 钱斌
机构地区 上海市第八人民医院普外科
出处 《中国实用外科杂志》 CSCD 北大核心 2009年第3期226-228,共3页 Chinese Journal of Practical Surgery
关键词 乳腺癌 神经内分泌肿瘤 breast cancer neuroendocrine carcinoma
分类号 R6 [医药卫生—外科学]
  • 相关文献

参考文献15

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二级参考文献4

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共引文献13

同被引文献104

  • 1张晓明,范嫏娣.乳腺神经内分泌癌5例临床病理分析[J].中国肿瘤临床,2005,32(13):755-758. 被引量：13
  • 2王少华,于泽平,李宁,杨小冬,黎介寿,张新华,孙桂秦.原发性乳腺浸润性导管癌组织中生长抑素受体和微血管密度的表达及其相关性[J].中华外科杂志,2006,44(19):1325-1326. 被引量：2
  • 3皋岚湘.伴神经内分泌分化的乳腺癌[J].诊断病理学杂志,1996,3(3):168-170. 被引量：7
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  • 10Hennessy BT,Gilcrease MZ,Kim E,et al.Breast carcinoma with neuroendocrine differentiation and myocardial metastases[J].Clin Breast Cancer,2007,7(11):892-894.

引证文献18

二级引证文献33

中国实用外科杂志
2009年 第3期

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