我院住院患者抗菌药物应用调查及与应用率的关系探讨

Use of Antibacterials in Inpatients of Our Hospital and the Rate of Patients Using Antibacterials

目的:探讨我院住院患者及其横断面抗菌药物应用率之间的关系。方法:采用横断面调查方法,统计我院2007年5月22～23日1040例住院患者的抗菌药物应用情况;随机抽取100份出院病历进行调查。结果:1040例住院患者中,有510例应用抗菌药物,占49.04%。各科室中以综合ICU应用率最高,达100%;其次为儿内科(86.05%)和肾内科(84.62%)。外科抗菌药物平均应用率(63.52%)明显高于内科(33.94%)。100例出院患者的抗菌药物应用率达81%,存在用药时机不当、预防性用药时间过长等现象。结论:我院住院患者抗菌药物应用率>住院患者横断面抗菌药物应用率>门诊患者抗菌药物应用率。需进一步加强抗菌药物合理应用监管。

OBJECTIVE： To study the correlation between the rate of inpatients using antibacterials and the cross- sectional rate of inpatients using antibaeterials. METHODS： A cross sectional study was conducted on the use of antibacterials in 1040 inpatients between May 22 and May 23 in 2007. Besides, the discharge case histories of 100 cases were collected randomly for an analysis. RESULTS： Of the total 1 040 inpatients, 510 （49.04%） used antimicrobials. The rate of inpatients using antibacterials in comprehensive ICU took the lead at 100%, followed by pediatric department （86.05%） and the department of nephrology （84.62 %）. The average rate of inpatients using antibacterials in surgery department was significantly higher than in the department of internal medicine （6a. 52% vs. 33.94% ）. 81% of the discharged cases used antibacterials. The irrational use of antibacterials manifested as improper timing of medication, prolonged use of antibacterials for prophylactic purpose etc. CONCLUSION： The proportion of the patients using antibacterials in descending order were inpatients, cross- sectional inpatients and outpatients. It is necessary to tighten control on the rational use of antimicrobials.