3416例宫颈分泌物支原体检测及药敏分析

Identification and Drug Susceptibility of Mycoplasma from Cervical Secretions:Analysis of 3 416 Cases

目的:了解我院女性生殖道支原体感染及药敏情况。方法:应用培养法对我院3416例女性生殖道炎症患者宫颈分泌物进行解脲支原体(Uu)和人型支原体(Mh)检测,同时测定其对抗菌药物的耐药性。结果:支原体感染的总阳性率为43.7%,其中Uu感染占40.0%,对环酯红霉素、美满霉素、强力霉素、交沙霉素敏感;Mh感染占0.7%,对强力霉素、美满霉素、交沙霉素敏感;Uu+Mh感染占3.0%,对强力霉素、交沙霉素、美满霉素敏感。结论:根据药敏结果合理用药,对防止支原体耐药株产生具有重要意义。

OBJECTIVE： To study the mycoplasma infection and the drug susceptibility of mycoplasma in cervical secretions from female genital tract in our hospital. METHODS： Ureaplasma urealyticum （Uu） and mycoplasma hominis （Mh） in cervical secretions sampled from 3 416 female genital tract inflammation cases in our hospital were identified by cultivation, and the antibiotic resistance was also detected. RESULTS： The total positive rate of mycoplasma was 43.7% ; Uu infection accounted for 40.0%, which was sensitive to Cycloate erythromycin, Minocycline, Deoxycycline, Josamycin; Mh infection accounted for 0.7%, which was sensitive to Deoxycycline, Minocycline and Josamycin; Uu ＋ Mh infection accounted for 3.0%, which was sensitive to Deoxycycline, Josamycin and Minocycline. CONCLUSION： Rational use of drugs based on drug susceptibility test is of importance to prevent the production of persister of mycoplasma.