牙本质基质蛋白-1的研究进展

Research advances of dentin matrix protein-1

牙本质基质蛋白-1是牙发育过程中一种非常重要的非胶原性基质蛋白,对牙本质的形成和矿化起着重要的作用,但其具体的作用机制有待于进一步的研究。下面就牙本质基质蛋白-1的表达定位、基因结构、生物学功能以及表达调控因素作一综述。

Dentin matrix protein-1 is an essential non-collagenous protein in dentinogenesis. It is believed to play a crucial role in the formation and mineralization of dentin, although the mechanism requires further study. The expression orientation, gene structure, biological function and regulation of dentin matrix protein-1 in dentin and bone was reviewed in this paper.