癫痫手术前SPECT的定位价值

The value of SPECT in localizing the epileptogenic foci

目的：了解单光子发射计算机断层扫描（ＳＰＥＣＴ）行局部脑血流检查在致痫灶定位中的应用价值。方法：对２４例癫痫患者行ＳＰＥＣＴ检查，结果采用目测和半定量分析两种方法进行判断。结果：１３／２４（５６％）的患者有目测的异常灌注区，其中１１／１３（８５％）与综合定位的结果相一致，半定量分析的方法可发现１２／１２的患者有异常灌注区，其中１０／１２（８３％）可得到与综合定位结果相一致的结论。统计学显示两种方法在阳性检出率和准确率上有显著差异。结论：ＳＰＥＣＴ在致痫灶的定位中有较高的应用价值，半定量分析的方法可明显提高ＳＰＥＣＴ对致痫灶的检出率。

Object:To evaluate the value of the SPECT in localized the epileptogenic fociMethod:Singlephoton emission computed tomography (SPECT) was used to study the regional cerebral blood flow(rCBF) in 24 cases with intractable epilepsy Visual and quantitative analysis were employed to examine the asymmetry between bilateral cerebral blood perfusionResult:Visual analysis can localized 13 of 24 patients and 11 of them were correctly localized Quantitative analysis can localized 12 of 12 patients and 10 of them were correctly localizedConclusion:The interictal SPECT examination is a valuable method in localized epileptogenic foci Quantitative analysis can make the result more reliable and sensitive