踝臂指数与冠状动脉病变程度的关系

Relationship between ankle - brachial index and the severity of coronary artery stenosis

目的研究踝臂指数与冠状动脉病变程度的关系。方法选取行冠脉造影检查者196例，按3种分组方法，根据冠脉病变支数分为：正常对照组、单支病变组、双支病变组和3支病变组；再把单支病变组和双支病变组合并为轻度病变组，3支病变组为重度病变组，把有冠状动脉病变者合并为冠心病组。比较以上各组间踝臂指数，同时探讨踝臂指数与冠脉Gensini积分的关系。结果正常对照组、单支病变组及双支病变组的踝臂指数明显高于3支病变组，但3组内比较差异无统计学意义。正常对照组和轻度病变组的踝臂指数明显高于3支病变组，但两组内比较差异无统计学意义。对照组和冠心病组比较差异无统计学意义。踝臂指数与冠脉Gensini积分成负相关（r=-0．25，P〈0．05）。结论踝臂指数与冠状动脉病变程度成负相关，踝臂指数≤0．9对冠状动脉严重病变有较好的预测价值。

Objective To study the relationship between ankle -brachial index （ABI） and the severity of coronary artery stenosis. Methods Totally 196 patients who underwent coronary angiography were included. Firstly, they were divided into four groups according to the number of coronary artery stenosis： normal control group, single vessel disease group, double vessels disease group and three vessels disease group. Secondly, combined the single vessel group and double vessels group into moderate coronary artery disease. So the patients were divided into three groups： normal control group, moderate coronary artery disease group and severe coronary artery disease group. Lastly, they were divided in two groups： normal control group and coronary artery disease group. ABI was compared among different groups. Results Compared with the three vessels disease group, ABI was significantly higher in normal control group, single vessel disease group and double vessels disease group, but no significant difference in ABI were found among the later three groups. Compared with the severe coronary artery disease group, ABI was significantly higher in normal control group and moderate coronary artery disease group, but no significant difference in ABI was found among the later two groups. Also, ABI was not significantly different between normal control group and coronary artery group. ABI was negatively correlated with Gensini score of coronary stenosis （ r = - 0.25, P 〈 0.05 ）. Conclusions ABI is negatively correlated with the degree of coronary artery stenosis. ABI ≤0.9 is a good predictor of severe coronary artery disease.