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急性冠脉综合征患者同型半胱氨酸水平及其与炎症关系的探讨 被引量:11

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摘要 目的探讨急性冠脉综合征(ACS)患者同型半胱氨酸(Hcy)的水平,以及Hcy与炎症因素的相关性。方法74例ACS患者其中急性心肌梗死(AMI)34例,不稳定型心绞痛(UA)40例;另设性别、年龄相匹配经冠脉造影排除冠心病的对照组33例。采取高效液相色谱分析法测定血浆中的Hcy,同时测定血浆中的血糖、血脂和血C反应蛋白(CRP)。结果血浆Hcy浓度AMI患者为(17.21±4.43)μmol/L,UA患者为(15.66±5.24)μmol/L,明显高于对照组的(8.99±3.75)μmol/L,差异有统计学意义(P<0.05);AMI组与UA组差异无统计学意义。ACS患者Hcy与CRP水平呈正相关(r=0.59,P=0.027)。结论高Hcy血症是ACS的一个独立危险因子,并且与引起ACS相关的炎症反应呈正相关。
出处 《广西医学》 CAS 2009年第2期211-212,共2页 Guangxi Medical Journal
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