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Ge-132对半乳糖性白内障的研究 被引量:1

A Study Of Germanium-132 on Galacoose Cataracts in Rats
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摘要 扼要叙述了Ge-132的性质、结构、生物学特性及临床应用等,重点介绍了Ge-132用于半乳糖性白内障的研究方法、结果和讨论,旨在通过Ge-132抑制与晶体混浊有关的糖基代末端产物(AGEs)形成,逆转糖基化蛋白为溶解状态,抑制或延缓白内障的发生和发展,为老年性或糖尿病性白内障开辟新的治疗途径。 This paper gives an outline on Ge-132's properties, structure, biological features, clinical applications, and attached importance to its study methods and results and discusses on the effect of Ge-132 on galactose induced cataractogenesis. It is aimed at inhibitting the formation of advanced glycation and products (AGEs) related to lens opacification by Ge-132, and at reverting glycated proteins into solubilization, which is effective on inhibiting or delaying the formation and the development of galactose-induced cataracts and explores new way for preventing senile or diabetic cataract.
作者 陈翠真 董冰
出处 《广东微量元素科学》 CAS 1998年第1期20-22,共3页 Trace Elements Science
关键词 锗132 半乳糖性白内障 有机锗化合物 白内障 Germanium-132, Galacoose Cataracts, Rat
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参考文献2

  • 1张树功.有机锗化合物的毒性[J].化学通报,1993(9):11-21. 被引量:19
  • 2K. Nakamura,K. Nomoto,K. Kariya,Y. Nakajima,H. Nishimoto,S. Uga,M. Miyata,T. Osawa,S. Kawakishi,N. Kakimoto. Prevention and reversible solubilization of advanced glycation and products (AGE) by organic germanium compounds as derivatives of amino acids[J] 1991,Amino Acids(2):263~278

二级参考文献1

  • 1张树功,Rare Met,1990年,14卷,6期,436页

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