烧伤病房细菌耐药性分析

Analysis of Bacterial Resistance in Burn Ward

目的:探讨烧伤病房病原微生物的种类及耐药性。方法:对2003年～2006年期间住院烧伤病人的创面或血液标本的细菌学培养结果进行回顾性调查。结果:共检出病原菌526株,以革兰氏阴性(G^-)杆菌居首(占55.89%),革兰氏阳性(G^+)球菌位居第二(占38.78%);526株中金黄色葡葡球菌、鲍曼不动杆菌、铜绿假单胞菌、肺炎克雷伯菌及阴沟杆菌菌株均在60株以上,鲍曼不动杆菌、铜绿假单胞菌、肺炎克雷伯菌及阴沟杆菌对头孢他啶等第三代头孢菌素及头孢哌酮/舒巴坦复合酶抑制剂的耐药率在35.68%～90.46%之间。结论:烧伤病房病原微生物仍以G^-杆菌居首,G^+球菌位居第二,耐甲氧西林金黄色葡葡球菌(MRSA)的发生率为100%,对头孢拉啶、氨基糖甙类及喹诺酮类和三代头孢菌素类的耐药率均在85%以上。

Objective： To explore the type and resistance of pathogenic microorganisms. Method： Retrospective investigation of bacteriological culture results was carried out for the patients＇ wound or blood specimens who were hospitalized from 2003 to 2006. Result： 526 strains were detected totally. Among of them, the most was gram - negative bacilli （55.98%）, the second was gram -positive pediococus （38.78%）. In the total 526 strains isolated from the patient＇ s wound and blood specimens, there were more than 60 kinds of strains included Portuguese golden staphylococcus aureus, Acinetobacter baccmannii, Pesudomonas aenginosa, Klebsieua pneumoniae, and enterobacter cloacue etc. The resistance rate of Acinetobacter baccmannii, Pesudomonas aeruginosa, Klebsieua pneumoniae, and Bacillus cloacae was in the range of 35.68% -90. 46% for the third generation cephalosporins （e. g Ceftazidime） and cefoperazone/sulbactam composite enzyme inhibitor. Conclusion： G^- bacillus still was in the first position of pathogenic microorganism and the second one was G^＋ cocci in the burn ward. The incidence rate of MethiciUin -resistant staphylococcus aureus （MRSA） was 100%. And the resistance rate of pathogenic microorganism for cefradine, aminoglycosides, quinolones and third - generation cephalosporins was more than 85%.