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系统生物学技术在微生物菌种改良中的应用 被引量：1

The application of systems biotechnology in microbial strain improvement
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摘要 生物工业不断探索新方法来改良微生物菌株。系统生物学技术的重要目标是通过大量的组学数据分析来阐明细胞功能,已经为菌种改进提供了新技术。作者综述了基因组、转录组、蛋白组、代谢物组以及代谢流组等系统生物学技术在微生物菌种改良中的应用,进而展望了基于系统水平改进微生物菌种的发展方向。 The biotechnology industry continuously explores new methods to improve the microbial strains. A central goal of systems biotechnology is the elucidation of cell function through analysis large amounts of Omics data,it has offered the novel technology for strain improvement. This review illustrates the applications of systems biotechnology, which involve genome, transcriptome, proteome, metabolome,and fluxome in microbial strain improvement. Finally the trend in strain improvement through systems biotechnology was discussed.
作者 李良智 咸漠 李小林 徐鑫
机构地区 中国科学院青岛生物能源与过程研究所 北京出入境检验检疫局
出处 《化工科技》 CAS 2009年第1期46-50,共5页 Science & Technology in Chemical Industry
基金 中国博士后科学基金资助项目(20070420702) 江苏省博士后资助计划项目(0702001C)
关键词 系统生物学技术 菌种改良 微生物 Systems biotechnology Strain improvement Microbe
分类号 TQ033 [化学工程] O643.3 [理学—物理化学]
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参考文献29

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同被引文献26

  • 1刘新星,谢建平,霍强,邱冠周.磁选育菌种新方法的研究——磁黄铁矿培养基选菌[J].金属矿山,2005,34(12):26-29. 被引量：2
  • 2王双才,李元坤,史光大,钟庆文,余平.氧化铜矿的处理工艺及其研究进展[J].矿产综合利用,2006(2):37-39. 被引量：49
  • 3舒荣波,阮仁满,温建康.黄铜矿生物浸出中钝化现象研究进展[J].稀有金属,2006,30(3):395-400. 被引量：26
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化工科技
2009年 第1期

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