期刊文献+

米卡芬净在治疗恶性血液病患者侵袭性真菌感染中的应用 被引量:1

下载PDF
导出
摘要 目的评价米卡芬净治疗血液肿瘤患者侵袭性真菌感染(IFI)的疗效及安全性。方法对同期收治的38例恶性血液病并发IFI患者应用米卡芬净治疗,观察疗效及安全性。结果38例总有效率为57.9%(22/38),确诊、临床诊断与拟诊者有效率分别为75.0%、63.2%、36.4%;38例均未出现临床和实验室不良反应。结论米卡芬净抗菌谱广,临床疗效及安全性好,可作为恶性血液病患者预防、经验性和抢先抗真菌治疗的药物。
出处 《山东医药》 CAS 北大核心 2009年第11期56-57,共2页 Shandong Medical Journal
  • 相关文献

参考文献10

  • 1黄晓军.血液病/恶性肿瘤患者侵袭性真菌感染的诊断标准与治疗原则(草案)[J].中华内科杂志,2005,44(7):554-556. 被引量:423
  • 2Hiemenz J, Cagnoni P, Simpson D, et al. Pharmacokinetic and maximum tolerated dose study of micafungin in combination with fluconazole versus fluconazole alone for prophylaxis of fungal infections in adult patients undergoing a bone marrow or peripheral stem cell transplant [J]. Antimicrob Agents Chemother, 2005,49 ( 4 ) : 1331 - 1336.
  • 3Tamura K,Urabe A,Yoshida M,et al. Efficacy and safety of micafungin, an echinocandin antifungal agent, on invasive fungal infections in patients with hematological disorders[ J]. Leuk Lymphoma, 2009 ,50( 1 ) :92-100.
  • 4Toubai T, Tanaka J. Efficacy and safety of micafungin in febrile neutropenic patients treated for hematological malignancies [ J]. Intern Med,2007,46( 1 ) :3-9.
  • 5Ikeda F. Antifungal activity and clinical efficacy of micafungin (funguard) [ J ]. Nippon Ishinkin Gakkai Zasshi, 2005,46 ( 4 ) : 217-222.
  • 6Joseph JM, Jain R, Danziger LH. Mieafungin:a new echinocandin antifungal[ J]. Pharnmcotherapy ,2007,27( 1 ) :53-67.
  • 7Nakagawa Y, lchii Y, Saeki Y, et al. Effect of liver and kidney function on migafungin disposition in patients with hematologic malignancies[ J ]. I Eur J Drug Mctab Pharmacokinet, 2008 , 33 ( 3 ) : 191-198.
  • 8Hebert MF, Townsend RW, Austin S, et al. Concomitant cyclospofine and micafuugin pharmacokinctics in healthy volunteers[ J]. j Clin Phamlaco1,2005,45 ( 8 ) :954 -960.
  • 9Kontoyiannis DP, Ratanatharathorn V, Young JA. Micafungin alone or in combination with other systemic antifungal therapies in hematopoietic stem cell transplant recipients with invasive aspeergillosis [ J ]. Transpl Infect Dis,2009,11 ( 1 ) :89-93.
  • 10Ikeda F,Tanaka S,Ohki H ,et al. Role of micaffungin in the antifiungal annamentarium [ J ]. Curr Med Chem, 2007,14 ( 11 ) : 1263- 1275:

共引文献422

同被引文献7

  • 1血液病/恶性肿瘤患者侵袭性真菌感染的诊断标准与治疗原则(修订版)[J].中华内科杂志,2007,46(7):607-610. 被引量:249
  • 2Auberger J, Lass-Florl C, Ulmer H, et al. Significant alterations in the epidemiology and treatment outcome of invasive fungal infections in patients with hematological malignancies. Int J Hematol, 2008,88:508-515.
  • 3Micafungin (Mycamine) for fungal infections. Med Lett Drugs Ther, 2005,47:51-52.
  • 4Quindas G, Eraso E, Javier Carrillo-Munoz A, et al. In vitro antifungal activity of micafungin. Rev Iberoam Micol, 2009,26:35-41.
  • 5Yoshida M. Guidelines for the management of deep mycosis in neutropenic patients. Nippon Ishinkin Gakkai Zasshi, 2004,45:209-215.
  • 6Yanada M, Kiyoi H, Murata M, et al. Micafungin, a novel antifungal agent, as empirical therapy in acute leukemia patients with febrile neutropenia. Intern Med, 2006, 45: 259-264.
  • 7朱飞波,周郁鸿.米卡芬净治疗恶性血液病合并侵袭性真菌病13例[J].实用临床医药杂志,2009,13(2):65-66. 被引量:7

引证文献1

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部