金铁锁中一个新的三萜皂苷(英文)

A New Triterpenoid Saponin from Psammosilene tunicoides

目的:研究金铁锁根的化学成分。方法:采用硅胶柱色谱、凝胶柱色谱和反相色谱分离纯化,利用ESI-MS,EI-MS,NMR确定化合物结构。结果:分离并鉴定了3个化合物,分别为3-O-β-D-galactopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→3)]-β-D-6-O-methylglucuronopyranosyl-gypsogenin(1),2α-hydroxy-ursolic acid(2),tormentic acid(3)。结论:化合物1为新化合物,化合物2、3均为首次从该属植物中分离得到。

AIM： To investigate the chemical constituents of Psammosilene tunicoides W. C. Wu et C. Y. Wu. METHODS： Compounds were isolated by silica gel, Sephadex LH-20 and Rp-C18 column chromatography and the structures were elucidated by ESI-MS, El-MS and NMR methods. RESULTS： Three compounds were isolated and identified as triterpenoid saponins： 3-O-β- D-galactopyranosyl-（1→2）-[β-D-xylopyranosyl-（1→3）]-β-D-6-O-methylglucuronopyranosyl-gypsogenin （1）, 2α-hydroxyursolic acid （2）, tormentic acid （3）.CONCLUSION： Compound 1 is a new triterpenoid saponin while compounds 2 and 3 are isolated from this genus for the first time.