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血浆置换治疗重型肝炎中不良反应的临床研究 被引量:4

The clinical study of adverse reactions of plasma exchange treatment on severe hepatitis
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摘要 目的:回顾性分析血浆置换治疗重型肝炎时不良反应发生的特点并探讨其防治对策。方法:对102例重型肝炎患者进行的326例次血浆置换治疗中发生不良反应的临床资料进行分析。结果:不良反应发生率为34.36%(112/326),其中,过敏反应最为常见,占69.64%;低血钙占9.82%,低血压占8.92%,插管处渗血占7.14%,继发感染占4.46%。结论:血浆置换治疗重型肝炎不良反应较为常见,但多为轻、中度反应,经及时治疗,均能缓解;根据不良反应的特点,有针对性地进行术前干预能够有效降低不良反应的发生率。 Objective: To retrospectively analyze the clinical features of adverse reactions of plasma exchange treatment in the patients with severe hepatitis and to discuss the preventions and treatments. Method: The clinical data of the adverse reactions of 326 therapeutic plasma exchange in 102 patients with severe hepatitis was analyzed. Results: The total inci- dence of adverse reactions was 34.36% (112/326), among which the most frequent adverse reactions was allergic reactions (69.64%), and others were low-calcium, low blood pressure, bleeding in the intubation and secondary infection(9.82%, 8.92%, 7.14%, 4.46%, respectively). Conclusion: Adverse reactions of plasma exchange treatment on severe hepatitis are common, but most of them are mild or moderate reactions, and can be relieved by timely treatments. The incidence of adverse reactions can be effectively reduced by countermeasures according to their characteristics.
出处 《中国医药导报》 CAS 2009年第8期52-53,共2页 China Medical Herald
关键词 血浆置换 重型肝炎 不良反应 Plasma exchange Severe hepatitis Adverse reactions
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