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奥曲肽、垂体后叶素治疗食管、胃静脉曲张出血82例临床分析

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摘要 目的 观察奥曲肽与垂体后叶素治疗食管、胃静脉曲张破裂出血临床疗效。方法82例患者,分为2组,其中奥曲肽治疗组44例,首先用奥曲肽0.1mg静脉推注(不少于5分钟),然后以25—30ug/h维持,垂体后叶素对照组38例,垂体后叶素18~20u静脉滴注,以0.2~0.4u/min维持。两组入选患者基本资料相似,具有可比性。结果治疗组,显效29例,有效6例,总有效率79%,无效9例,占21%。对照组,显效21例,有效7例,总有效率74%,无效10例,占26%。两组显效率比较,总有效率比较,均无显著性差异。结论本组两者比较奥曲肽与垂体后叶素治疗食管、胃静脉曲张破裂出血无明显差异,止血率前者稍优于后者,但对于中老年患者及原有心血管疾病患者,应以奥曲肽类生长抑素为首选。
出处 《西南军医》 2009年第2期290-291,共2页 Journal of Military Surgeon in Southwest China
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