摘要
高效毛细管电泳分离定量测定环孢菌素的结果与高效液相色谱结果相一致。本文对影响分离的主要因素：ＳＤＳ、缓冲液浓度、有机溶剂及ｐＨ进行了选择和优化，环孢菌素Ａ、Ｂ、Ｃ、Ｄ、Ｇ５个组分得以基线分离。为环孢菌素Ａ的分离定量分析提供了一种新方法。
Cyclosporin A was analysed by high performance capillary electrophoresis (HPCE). The experiment show that the result of HPCE is identical to that of HPLC. By optimizing the major factors SDS, buffer concentration, organic solvent and pH, a new method was established. The method can be used to separate cyclosporin A, B, C, D and G.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
1998年第1期21-23,共3页
Chinese Journal of Antibiotics
关键词
环孢菌素
高效毛细管电泳
成分
Cyclosporin A, B, C, D, G
High performance capillary electrophoresis
