脑SPECT显像在突发性聋患者脑血流灌注研究中的价值

The Value of Brain SPECT in the Study of rCBF on the Patients with Sudden Deafness

目的：为研究突聋的发病与局部脑血流量（ｒＣＢＦ）的关系以及治疗前后听觉功能变化的机制。方法：应用单光子发射型计算机断层（ＳＰＥＣＴ）显像，比较了２０例突聋患者治疗前后ｒＣＢＦ摄取计数（ＲＣ）和摄取比值（ＲＩ）。结果：①治疗前患侧ＲＣ较健侧有显著性降低，②治疗后ＲＩ较治疗前有显著性增高。结论：①突聋发病与局部脑组织（颞叶）血流灌注量降低有关，②本项研究治疗有效，并且治疗后颞叶听觉中枢灌注状态改善与临床听觉功能好转一致。

Purpose:To study the relationship between the cause of sudden deafness(SD) and rCBF,and to detect the mechanism of hearing changes after therapy.Methods:The rCBF regional counts(RC) and regional index(RI) were measured to compare the rCBF changes in the patients with SD before and after treatment.Results:The RC of affected temple was decreased obviously in comparison with the healthy side(P<0001).The RI of posttreatment showed a significant increase over pretreatment (P<0001).Conclusions:The cause of SD was interrelated with the decrease of rCBF and the hearing recovery was correlative to rCBF improvement.