超声多普勒Tei指数与冠状动脉病变严重程度的关系

Relationship between of Tei index and the severity in patients with coronary artery disease

目的探讨多普勒超声Tei指数与冠状动脉病变严重程度之间的关系。方法选取临床初步诊断为冠心病患者100例，行定量冠状动脉造影（QCA）和脉冲多普勒超声心动图采集二尖瓣和主动脉瓣血流频谱，计算出Tei指数，比较不同程度的冠状动脉病变和Tei指数之间的关系。结果100例中有70例经冠状动脉造影诊断为冠心病，30例冠状动脉造影阴性，排除冠心病；随着冠状动脉狭窄程度的加重，Tei指数有上升趋势（0．39±0．03～0．48±0．06），冠状动脉重度狭窄组Tei指数（0．48±0．06）较冠状动脉轻度狭窄组（0．42±0．05）比较，差异有统计学意义（q=3．21，P〈0．05），但冠状动脉轻度狭窄组（0．42±0．05）与冠状动脉无狭窄组（0．39±0．03）比较差异无统计学意义（q=2．21，P〉0．05）；Gemini积分41～80分、≥81分组与1—40分组的Tei指数比较差异有统计学意义（q=3．28、3．31，均P〈0．05）。结论检测Tei指数可以评估冠状动脉病变的严重程度。

Objective To investigate the relationship between Tei index and the extent of coronary artery disease. Methods 100 cases who underwent quantitative coronary angiography（QCA） were enrolled in this study, Frequency spectrum of blood flow of mitral valve and aortic valve was gathered in Pulse Doppler,from which Tei index was calculated. Results 70 patients of 100 eases with coronary angiography were diagnosed coronary heart disease 70% （70/100） ;coronary angiography in 30 patients with negative excluded coronary heart disease;with the degree of coronary artery stenosis increased Tei index rising trend （0. 39± 0.03 - 0.48 ± 0. 06） ;Severe coronary artery stenosis Tei index （0. 48 ± 0. 06） than the mild coronary artery stenosis （0. 42 ± 0. 05 ） increased significantly （ q = 3.21, P 〈 0. 05） ,but mild eorenary artery stenosis （0. 42±0. 05） and no narrow group（0. 39 ±0. 03） there was no signifieant difference （ q = 2. 21,P 〉 0. 05 ） ; A comparison of Tei index between Gensini integral 41 to 80 cent. ≥ 81 cent and 40 cent were significant different（q =3.28,3.31 ,all P〈0. 05）. Conclusion Tei index was postive correlated with the extent of coronary artery disease.