冠心病患者心理社会因素与血清脂质水平的相关性研究

Serun lipid level and psychosocial factors in coronary disease

对４６例冠心病患者和健康对照者进行了Ａ型行为、生活事件及焦虑和抑郁的评定。结果显示，病例组的Ａ型行为者，应激性生活事件数目及焦虑和抑郁评分，明显高于对照组；病例组的血清胆固醇水平与Ａ型行为、负性生活事件及焦虑和抑郁评分呈正相关，血清甘油三酯水平与Ａ型行为和焦虑分呈正相关。

Objective:To study the relationship between psychosocial factors and serum lipid levels in coronary diseases.Method: 46 patients with coronary heart disease were assessed with the type A behavioural inventory,life events scale,anxiety and depression scale and compared with 46 matched healthy control subjects.Results: The scores of type A behaviour,life stressful events,anxiety and depression in the coronary disease group were significantly higher than that of the control.In the disease group,the serum total cholesterol level showed positive correlation with scores of type A behaviour,negative life events,anxiety and depression while serum triglyceride level correlated positively with scores of type A behaviour and anxiety.Discussion: The results suggest that psychosocial factors are important in the pathogenesis of coronary disease.