摘要
A reaction for the synthesis of rothindin,a naturally occurring isoflavone glycoside,between the 7-hydroxy-3′,4′-methylenedioxyisoflavone(ψ-baptigenin),which are prepared in good yield from a Houben-Hoesch reaction,and 1-bromo-2,3,4,6-tetra-O-acetyl——D-glucopyranose at the NaHCO3/KCl alkaline solutions in presence of the phase transfer catalyst tri(3,6-dioxaheptyl)amine(TDA-1) is discussed.The formation of the corresponding glucosides are confirmed by IR and 1HNMR studies,with a 82% yield of O-glycoside conjugate.
A reaction for the synthesis of rothindin, a naturally occurring isoflavone glycoside, between the 7-hydroxy-3＇, 4＇- methylenedioxyisoflavone （ψ- baptigenin） ,which are prepared in good yield from a Houben-Hoesch reaction,and 1-bromo-2,3,4, 6-tetra-O-acetyl- -D-glucopyranose at the NaHCO3/KCl alkaline solutions in presence of the phase transfer catalyst tri （3,6- dioxaheptyl） amine （ TDA-1 ） is discussed. The formation of the corresponding glucosides are confirmed by IR and ^1HNMR studies, with a 82% yield of O-glycoside conjugate.
出处
《化学研究与应用》
CAS
CSCD
北大核心
2009年第3期393-395,共3页
Chemical Research and Application
基金
天津理工大学资助项目(601002001)
