自组装分子印迹单层膜修饰电极对L-丝氨酸的检测

Determination of L-Serine with Self-assembled Molecular Imprinted Monolayer Modified Electrode

以电沉积多孔金膜为基底,L-丝氨酸为模板分子,L-半胱氨酸为功能单体构建了信号放大的自组装分子印迹单层膜修饰电极。电极对L-丝氨酸浓度响应的线性范围为5.0×10-6～2.0×10-4mol/L,检出限为4.8×10-7mol/L,灵敏度为215 mA·L·mol-1。由于多孔金膜有效增加了模板分子的固定量,印迹电极响应性能较无多孔金膜修饰的印迹电极有明显提高。

A new amplified self-assembled modified electrode for L-serine recognition, with molecular imprinted monolayer on electrodeposited porous gold film was developed. L-cysteine was used as assembling monomer and L-serine was used as template. Its stable response to L-serine was achieved within 5 min, covering a linear range from 5.0 ×10^-6 -2. 0×10^-4 mol/L, with a sensitivity of 215 mA · L· mol^-1, and a detection limit of 4. 8 ×10^-7 mol/L. Because of the effective increase of template molecular on the electrode surface, the analytical performance of this imprinted electrode was better than the imprinted electrode without porous gold film modified.