绝经过渡期功能失调性子宫出血78例临床治疗分析

Analysis on clinical features and treatment of 78 women with dysfunctional uterine bleeding in menopausal transition period

目的:研究绝经过渡期功能失调性子宫出血的临床特点,探讨有效治疗方式。方法:回顾性分析2006年4月～2007年7月,经本院门诊治疗的78例绝经过渡期功能失调性子宫出血患者的临床资料。结果:患者平均年龄(46.97±2.23)岁(42～54岁),出血时间11～180天,出现中重度贫血11例,选择刮宫手术治疗32例,反复多次手术治疗4例,应用药物治疗时间为(2.34±1.73)周期(1～10周期),选择曼月乐治疗2例。结论:绝经过渡期功能失调性子宫出血是下丘脑-垂体-卵巢轴失调导致的无排卵性出血,治疗方法不能仅仅局限于止血,而应进行内分泌药物调节和长期随访观察。

Objective： To analyze the clinical features of dysfunctional uterine bleeding in menopausal transition period. Methods： From April 2006 to Jule 2007, clinical data of 78 cases with dysfunctional uterine bleeding in menopausal transition period in Beijing Chaoyang Hospital were analyzed retrospectively. Results： The mean age of cases was （46. 97 ± 2.23） years （42 -54 years） . The time of vaginal bleeding was 11 - 180 days. 11 cases were found severe anaemia. 32 cases underwent dilatation and curettage, and the surgery was carried out many times on 4 cases. The drug was administered on （2. 34 ± 1.73） cycles （ 1 - 10 cycles） . 2 cases chose mirena. Conclusion： Dysfunctional uterine bleeding in menopausal transition period is anovulatory bleeding induced by hypothalamic - pituitary - ovarian axis disturbance. Hormonal regulation and long - term follow - up may play a role in the treatment of dysfunctional uterine bleeding.